摘要 |
Compounds of the formula: <CHEM> in which Y is -(CH2)n- where n is one of the integers 1,2,3 or 4 or -CH2@@-CH2-; Z is -@-SO2- or -SO2@- where R is hydrogen, alkyl, polyfluorinated alkyl, -CN, cyanoalkyl, cycloalkyl or cycloalkylalkyl; R<2>, R<3>, R<4>, R<5>, R<6> and R<7>, independently, are hydrogen, alkoxy, trifluoromethyl or halo; R<8> is hydrogen or alkyl; R<9> is alkyl; R<1><0> is alkyl; m is one of the integers 0 or 1; p is one of the integers 0, 1, 2 or 3; and s is one of the integers 0 or 1; or a pharmaceutically acceptable salt thereof, are useful as anti-arrhythmic agents. |