发明名称 |
Beta-lactam compounds and their production. |
摘要 |
<p>Described are amino acid compounds of the formula: <CHEM> wherein R is a lower alkyl group, R1 is a hydrogen atom or a protecting group for carboxyl, R2 is a hydrogen atom, a protecting group for amino, an optionally substituted allyl group of the formula: <CHEM> (wherein R3 and R4 are each a hydrogen atom, a lower alkyl group or an aryl group), a beta-hydroxyethyl group in which the hydroxyl group is optionally protected, a formylmethyl group in which the formyl group is optionally protected, a carboxymethyl group in which the carboxyl group is protected or a 2-furylmethyl group and X is an optionally protected carboxyl group, a hydroxymethyl group in which the hydroxyl group is optionally protected or a substituted mercaptomethyl group of the formula: -CH2SR5 (wherein R5 is an aryl group or an ar(lower)alkyl group), which are useful intermediates in the synthesis of 1-alkylcarbapenem compounds.</p> |
申请公布号 |
EP0229384(A2) |
申请公布日期 |
1987.07.22 |
申请号 |
EP19860117997 |
申请日期 |
1986.12.23 |
申请人 |
SUMITOMO PHARMACEUTICALS COMPANY, LIMITED |
发明人 |
SUNAGAWA, MAKOTO SUMITOMO PHARMACEUTICALS CO.,LTD.;NOZAKI, YOSHIHITO SUMITOMO PHARMACEUTICALS CO.,LTD;SASAKI, AKIRA SUMITOMO PHARMACEUTICALS CO.,LTD.;MATSUMURA, HARUKI SUMITOMO PHARMACEUTICALS CO.,LTD |
分类号 |
C07C67/00;C07C229/22;C07C229/24;C07C239/00;C07C271/22;C07C313/00;C07C319/20;C07C323/57;C07C323/58;C07C323/63;C07D205/08;C07D307/52;C07D309/30;C07D405/06;C07D477/00 |
主分类号 |
C07C67/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|