| 摘要 |
PURPOSE:The titled preparation that contains antibiotic: SF-2370 as an active ingredient. CONSTITUTION:The objective hypotensive and diuretic preparation contains, as an active ingredient, an antibiotic: SF-2370, which is pale-yellow, crystalline, and neutral, has a molecular formula of C27H21N3O5, a melting point of 256 deg.C, a specific rotatory power: [alpha]<25>D=+57 deg. (C=0.1 in methanol), being positive to the Greig-Leaback reaction, negative to the ninhydrin reaction, soluble in pyridine, sparingly soluble in methanol and insoluble in water. The preparation is usable intravenously as well as orally. The dose ranges from 10 to 100mg/ person/day. EFFECT:Since it has physiological actions of hypotension and diuresis independently from each other, the active ingredient need not be combined with other hypotensives or diuretics. Even when it is given in a single form, the drug reduces the amount of body fluid and positively reduces the blood pressure, it is an ideal remedy for hypertension. |
