摘要 |
The title compds. of formula (I) or its pharmaceutically acceptable salts are new. (I) are prepd. by reacting (II) with Het-Zn-Cl in the presence of tetrakis (triphenylphosphine) Pd(o) catalyst at 25-80 deg. C. In the formula, Het is imidazolyl or triazolyl gp. (opt. subst. by 1-2 methyl), pyridyl gp. (opt. substd. by 1-2 methyl or hydroxy); R, R1, R2, R3, R4 and R5 are H or CH3 ; Q is leaving gp.. (I) are useful for treatment of cardic insufficiency.
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