发明名称 Dioxane hexenoic acids.
摘要 <p>The invention concerns novel 1,3-dioxane hexenoic aids and related carboxytic acid esters and alkanesulphonamides of the formula I in which X is oxy or thio, R' is hydrogen, halogeno, trifluoromethyl, cyano and nitro and R&lt;Sup&gt;2&lt;/Sup&gt; is hydrogen, together with their pharmaceutically acceptable salts. The invention also concerns processes for the production of the novel compounds and pharmaceutical compositions containing the compounds for use in the treatment of various diseases in which thromboxane A&lt;Sub&gt;2&lt;/Sub&gt; (TXA&lt;Sub&gt;2&lt;/Sub&gt;) is implicated.</p>
申请公布号 EP0228887(A2) 申请公布日期 1987.07.15
申请号 EP19860310019 申请日期 1986.12.22
申请人 IMPERIAL CHEMICAL INDUSTRIES PLC 发明人 BROWN, GEORGE ROBERT;SMITHERS, MICHAEL JAMES
分类号 A61K31/34;A61K31/357;A61K31/38;A61K31/381;A61P7/02;C07D319/00;C07D333/00;C07D407/04;C07D409/04;(IPC1-7):C07D407/04;A61K31/335 主分类号 A61K31/34
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