| 摘要 |
NEW MATERIAL:A compound of formula I (R<1> is H, lower alkyl; R<2>, R<3> are lower alkyl, aralkyl, alkenyl, alkinyl, cycloalkyl, aryl, heterocyclic group, or they may incorporate to form alkylene group). EXAMPLE:3-(1,3-Dithiethane-2-ylidene)-2,4-hexanedione. USE:A remedy for hepatopathy. PREPARATION:A base such as sodium hydroxide and carbon disulfide are allowed to act on a beta-diketone of formula II in a polar solvent to form a ketene mercaptide of formula III, which is allowed to react with a dihalogenomethane of formula IV at 0 deg.C to room temperature for 0.5-3hr to give the compound of formula I. |
