A process is herein disclosed for producing a slow release composite comprising grinding and mixing mechanically in a frozen state one or more polypeptides, one or more proteins and one or more physiologically active substances shaping the blend into a desired form and compressing at a pressure of from 100 to 20,000 kg/cm2 to thereby produce a slow release composite having the physiologically active substances encapsulated therein.
申请公布号
DE3202255(C2)
申请公布日期
1987.07.09
申请号
DE19823202255
申请日期
1982.01.25
申请人
JAPAN ATOMIC ENERGY RESEARCH INSTITUTE, TOKIO/TOKYO, JP