| 摘要 |
<p>A novel glycoprotein growth factor isolated from prostate gland of rats having the following characteristics: (a) molecular weight of about 25 kDa as determined by nonreduced sodium dodecylsulfate polyacrylamide gel electrophoresis; (b) sensitivity to reduction by beta -mercaptoethanol to form subunits of about 6-8 kDA with substantial loss of mitogenic activity; (c) isoelectric point of about 5.0 as determined by isoelectric focusing; (d) acid- and heat-stable; (e) unstable to proteolytic action of trypsin and pronase; (f) essentially free of transforming growth factor activity; (g) a defined amino acid composition; and (h) having mitogenic activity against NRK cells. p</p> |
