CAT LEUKEMIA VIRUS VACCINE

摘要

Infectious recombinant viruses that contain a chimeric FeLV envelope gene and are useful as feline leukemia vaccines are described. The viruses are made by transfecting susceptible mammalian cells with DNA of the virus and an insertion vector that includes a chimeric gene comprising a promoter that is active in the cells, a translation start codon, and a DNA sequence that encodes an FeLV envelope protein and is under the control of the promoter. Vaccines composed of such infectious recombinant viruses and a parenteral vehicle or of inactivated preparation of cells or cell fractions which had been infected with said recombinant viruses are also described.