发明名称 ANTIBACTERIAL COMPOUND
摘要 NEW MATERIAL:The compound of formula I [R<0> is H, nitrogen-containing heterocyclic group, acyl or amino-protecting group; Z is S, S O, O or CH2; R<4> is H, methoxy or formamide; R<13> is H, methyl, OH or halogen; A is (substituted) condensed triazolio], its salt or ester. EXAMPLE:7beta-[2-(2-Amionothiazol-4-yl)-2(Z)-methoximinoacetamido]-3-[(5- methyl-[1,2,4]triazolo[1,5-a]pyidinium-1-yl)methyl]-3-cephem-4-carboxy late of formula II. USE:An antibacterial agent. PREPARATION:The objective compound can be produced by reacting the compound of formula III (R<5> is OH, acyloxy, carbamoyloxy or halogen) or its salt or ester with a (substituted) condensed triazole compound or its salt.
申请公布号 JPS62149684(A) 申请公布日期 1987.07.03
申请号 JP19860206574 申请日期 1986.09.01
申请人 TAKEDA CHEM IND LTD 发明人 YOSHIMURA YOSHINOBU;HASHIMOTO NAOTO;KISHIMOTO SHOJI
分类号 A61K31/545;A61P31/04;C07D471/04;C07D487/04;C07D501/46;C07D519/00;C07D519/06 主分类号 A61K31/545
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