摘要 |
NEW MATERIAL:The compound of formula I [R<0> is H, nitrogen-containing heterocyclic group, acyl or amino-protecting group; Z is S, S O, O or CH2; R<4> is H, methoxy or formamide; R<13> is H, methyl, OH or halogen; A is (substituted) condensed triazolio], its salt or ester. EXAMPLE:7beta-[2-(2-Amionothiazol-4-yl)-2(Z)-methoximinoacetamido]-3-[(5- methyl-[1,2,4]triazolo[1,5-a]pyidinium-1-yl)methyl]-3-cephem-4-carboxy late of formula II. USE:An antibacterial agent. PREPARATION:The objective compound can be produced by reacting the compound of formula III (R<5> is OH, acyloxy, carbamoyloxy or halogen) or its salt or ester with a (substituted) condensed triazole compound or its salt. |