发明名称 ANALGESIC ANTIINFLAMMATORY FOR EXTERNAL USE
摘要 PURPOSE:The titled preparation that is prepared by adding a small amount of corticosteroid to ethylene salicylate and L-menthol, as active ingredients, thus sustaining anti-inflammatory analgesic effect to the subcutaneous site to which the preparation is applied for a relatively prolonged period of time. CONSTITUTION:2-100pts.wt. of ethylene salicylate, 0.02-5pts.wt. of cor ticosteroid such as dexamethasone, prednisolone, hydrocortisone or be tamethasone, 10-100pts.wt. of L-menthol and 1-20pts.wt. of tocoferol acetate, which intensifies anti-inflammatory effect by peripheral vasodilation are used to form an aerosol, solution and other perparations of anti-inflammatory analge sic for external use. Further, a solublizer such as ethanol may be added to the composition so that the viscosity is decreased to facilitate jetting and spread ing and the precipitation of components from the thick solution is prevented during low-temperature storage.
申请公布号 JPS62149620(A) 申请公布日期 1987.07.03
申请号 JP19860202270 申请日期 1986.08.27
申请人 SHIONOGI & CO LTD 发明人 SAITO IZUMI;SHIROYAMA HIROKUNI;ASANUMA FUJIO;HIROSE KATSUMI;EGAWA SHOHEI
分类号 A61K31/045;A61K9/08;A61K9/12;A61K9/70;A61K31/57;A61K31/60;A61P25/04;A61P29/00;A61P43/00 主分类号 A61K31/045
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