| 摘要 |
<p>Substituted 2,3,4,9-tetrahydro-1H-carbazole-1-acetic acid derivatives and methods for their preparation and use are disclosed. The compounds are useful analgesic and anti-inflammatory agents. The derivatives are acids of formula I below or their salts. <CHEM> In formula (I) R<1>, R<2>, R<3>, R<4>, R<5> and R<6> are hydrogen or lower alkyl or R<3> and R<4> are joined together to form (CH2)m or R<5> and R<6> are joined together to form -CH=CH-CH=CH-, (CH2)n, -CH=CH=O- or -CH=CH-S-, R<8> and R<1><0> are independently hydrogen, lower alkyl or halogen, R<9> is hydrogen or lower alkyl, m is 2 to 3 and n is 2 to 4.</p> |
