Process for preparing (S)-alpha-methylarylacetic acids.

摘要

The invention relates to a process for preparing (S)-alpha-methylarylacetic acids from mixtures, such as racemic mixtures, of (R)- and (S)-alpha-methylarylacetic acid esters by enantiospecific hydrolysis using extracellular lipases of microbial origin (EC 3.1.1.3). Preferably S-2-(6-methoxy-2-naphthyl)-alpha-methylacetic acid is prepared (S-Naproxen).