发明名称 Process to improve the expression of eucaryotic protein.
摘要 The expression of a eucaryotic protein is improved by introducing the cDNA coding sequence of a eucaryotic gene at least one intron naturally occurring in the corresponding gene. This cDNA is then cloned in procaryotes, the cloned cDNA is recovered and if necessary introduced into a eucaryotic cell which translates the cDNA into the desired protein.
申请公布号 EP0227064(A1) 申请公布日期 1987.07.01
申请号 EP19860117750 申请日期 1986.12.19
申请人 ROCHE DIAGNOSTICS GMBH 发明人 SCHUMACHER, GUENTER, DR.;HIRTH, PETER, DR.;BUCKEL, PETER, DR.
分类号 C12N9/64;A61B19/00;C12N9/72;C12N15/00;C12N15/09;C12N15/67;C12N15/85;C12P21/00;C12R1/91 主分类号 C12N9/64
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