| 摘要 |
Compounds of the formula <IMAGE> in which R denotes a carbocyclic or heterocyclic aryl radical, R1 represents lower alkyl, one of the groups R2 and R3 represents lower alkyl and the other represents lower alkyl, cyano or amino, X represents oxygen or the group -NH-, and Alk denotes alkylene substituted by a carbocyclic aryl which separates the group X from the ring nitrogen atom by at least two carbon atoms, Y represents alkylene or the groups -CH(OH)- or -C(=O)- or denotes a single bond, and Ar1 represents a monocyclic aryl or heteroaryl radical, and their salts can be used as coronary dilators and antihypertensives and are prepared in a manner known per se. |
