发明名称 |
Stabilization of glucose isomerase |
摘要 |
Extracellular enzymes are stabilized with a carboxyalkylated or phosphonoalkylated polymer having a molecular weight of at least 500 Daltons. Exemplified is the stabilization of the enzyme glucose isomerase used in a process to convert D-glucose to D-fructose. In a preferred embodiment of the invention the feedstream containing the substrate is contacted initially with the stabilizer and then with the enzyme. In this system the stabilizer and enzyme are maintained in separate reactors. This separation, advantageously, results in a higher half-life for the enzyme.
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申请公布号 |
US4675292(A) |
申请公布日期 |
1987.06.23 |
申请号 |
US19850707774 |
申请日期 |
1985.03.04 |
申请人 |
THE DOW CHEMICAL COMPANY |
发明人 |
HOUTCHENS, ROBERT A.;CHENG, ROBERTA C.;MCCOY, KAREN M.;EPSTEIN, CAROL C.;MOLL, NORMAN G. |
分类号 |
C12N11/00;C12N9/96;C12N11/04;C12N11/08;C12P19/24;(IPC1-7):C12P19/24 |
主分类号 |
C12N11/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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