4,6-Pregnadien- und 1,4,6-Pregnatrien-17alpha-ol-3,20-dione und Verfahren zu ihrer Herstellung

摘要

The invention comprises steroids of the general formula: wherein the dotted line represents the optional presence of a double bond, X represents a hydrogen or halogen atom, R represents a hydroxy or keto group and R1 represents an alkyl group containing 1 to 5 carbon atoms, and the preparation thereof by reacting the corresponding 4-pregnenes and 1, 4-pregnadienes with chloranil. Therapeutic compositions which may be in the form of a pill, tablet, capsule, solution, suspension or injectable solution or suspension and may be used for the treatment of arthritis and related diseases, contain as the active ingredient steroids of the above general formula.