GAMMA-EMITTING RECEPTOR-BINDING QUINUCLIDINYL BENZILATES METHODS OF PREPARATION THEREOF AND IMAGING AND ASSAY METHODS UTILIZING SAME

摘要

Compounds of the formula: (FORMULA) wherein R is phenyl, cyclopentyl or cyclohexyl, Ru is H or lower alkyl preferably CHu, X is in the ortho-, meta-or para- position, and is selected from the group consisting of sI sI, I, sF, sBr, sBr, NHu, and -N=N-N (FORMULA) , Ru is in the 2, 3 and 4 position and is selected from the group consisting of H and lower alkyl, and Z s is an anion; or free amine form thereof; methods for their production and compositions for and methods of tissue radio-assay and radio-external imaging utilizing said radioisotope containing compounds.