17 alpha -alkyl-17 beta -hydroxy-1 alpha -methyl-4-androsten-3-ones, their production and use pharmaceutically

摘要

17 alpha -Alkyl-17 beta -hydroxy-1 alpha -methyl-4-androsten-3-ones of the formula <IMAGE> wherein R is a straight-chain alkyl residue of 3-8 carbon atoms, i.e., C3-8-n-alkyl, are pharmacologically active compounds distinguished by antiandrogenic activity, especially upon topical application.