| 摘要 |
PURPOSE:To economically obtain high-purity <14>C-pyrroloquinolinequinone by a simple opration in high yield, by cultivating a cell, especially a microorganism by the use of <14>C-methanol as a carbon source. CONSTITUTION:A microorganism belonging to a methanol assimilating mold, capable of producing pyrroloquinolinequinone, is cultivated in a nutritive medium using methanol labelled by <14>C as a carbon source, pyrroloquinolinequinone labelled by <14>C is formed in a culture mixture and collected. The concentration of <14>C methanol to provide good result is 1-50ml/l, preferably 5-30ml/l. The culture is carried out under an aerobic condition. |
