摘要 |
<p>A transdermal delivery system for a vasoactive substance includes, by weight, about 30 to 70% of a medically-acceptable liquid silicone rubber, about 5 to 25% of a vasoactive substance, about 0.1 to 2.0% of a gelling agent, about 2 to 15% of a material which swells as water is absorbed from the stratum corneum and about 5 to 35% of a mixture comprising one or more solvents, viscosity reducers and skin penetration enhancers including, by weight of the entire delivery system, about 5 to 25% of a solvent, about 0 to 5% of a viscosity reducer and about 5 to 25% of a skin penetration enhancer.</p> |