发明名称 PROCESS FOR PREPARING NOVEL GUANIDINOTHIAZOLE COMPOUNDS
摘要 PROCESS FOR PREPARING NOVEL GUANIDINOTHIAZOLE COMPOUNDS Process for preparing novel guanidinothiazole compounds of the general formula: <IMG> wherein R represents a hydrogen atom or a lower alkyl group; R1 represents an amino group, a lower alkyl group, a halogeno lower alkyl group, a substituted- or unsubstituted-aryl group, a mono- or di-lower alkylamino group, an arylamino group or an aralkylamino group; R2 represents a hydrogen atom, a lower alkyl group, a lower alkenyl group or a lower alkynyl group; Y represents a sulfur atom or a methylene sroup; m and n, each represents an in-eger of 1 - 3; and the pharmacologically acceptable acid addition salts thereof. The guanidinothiazole compounds having gastric acid secretion inhibitors.
申请公布号 CA1222763(B) 申请公布日期 1987.06.09
申请号 CA19860521982 申请日期 1986.10.31
申请人 YAMANOUCHI PHARMACEUTICAL CO. LTD. 发明人 HIRATA, YASUFUMI;YANAGISAWA, ISAO;ISHII, YOSHIO;TSUKAMOTO, SHINICHI;ITO, NORIKI;ISOMURA, YASUO;TAKEDA, MASAAKI
分类号 C07D277/20;A61K31/425;A61K31/426;A61P1/00;A61P1/04;A61P43/00;C07D277/40;C07D277/48;(IPC1-7):C07D277/38 主分类号 C07D277/20
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