PREPARATION OF 1-SUBSTITUTED AZETIDINE-3-OL DERIVATIVES

摘要

K 1946 FF PREPARATION OF 1-SUBSTITUTED AZETIDINE-3-OL DERIVATIVES A process for the preparation of 1-substituted azetidin-3-ol derivatives of formula: I in which R1 represents an arylmethyl group, and R2 represents a hydrogen atom or an alkyl, aryl or aralkyl group in which the alkyl moiety contains up to 8 carbon atoms, by cyclising a solution in triethylamine of an aminoalcohol of formula II in which Hal represents a halogen atom and R1 and R2 are as defined above. me use of such derivatives as intermediates for the preparation of azetidine-3-carboxylic acid derivatives. BK24.006