| 摘要 |
NEW MATERIAL:A compound expressed by formula I (R represents heterocyclic group). EXAMPLE:Bis(2-hydroxy-6-isopropyltropon-3-yl)-(thiophen-2-yl)methane. USE:An anticacer agent. PREPARATION:For example, a compound expressed by the formula RCH (OC2H5)2 (example; thiophenecarbaldehyde-dithioacetal, etc.) is reacted with hinokitiol expressed by formula II in a solvent (example; xylene, etc.) or without using any solvent in the presence or absence of a catalyst (preferably potassium t-butoxide) usually at 150-180 deg.C for 1-10hr. As for the starting material, nor mally 0.5-1mol of the former and preferably 0.01-1mol catalyst are used based on 1mol of the latter.
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