| 摘要 |
NEW MATERIAL:A benzothiazine derivative of formula I (R<1> is H, lower alkyl, halogen, nitro, hydroxy, lower alkoxy, lower alkanoyloxy, amino, lower- alkylamino or lower alkoxycarbonyl; R<2> is H, lower alkyl, C3-C6 cycloalkyl; R<3> is H, lower alkyl, hydroxy; R<4> is H, lower alkyl; A, B are 1-6C alkylene) and its salts. EXAMPLE:3, 4-Dihydro-2-[ 5-methoxy-2-[4-[N-methyl-N-[2-[3, 4-methylenedioxy) phenoxy]ethyl]amino]butoxy]phenyl}-4-methyl-3-oxo-2H-1,4-benzothiazine. USE:It is used for circulatory diseases such as hypertension or thrombosis. PREPARATION:For example, a reaction is carried out as shown in the reaction equation to give the compound of formula I. |
