| 摘要 |
Peptides represented by the formula: <IMAGE> wherein: X represents Met, Met(O), Nle, or Ile; Y represents a cystine residue or an alpha -amino suberic acid residue; Z represents Gly or Ala; m, n, and p each represent 0 or 1; A represents Ser, Ser-Ser, Arg-Ser-Ser, Arg-Arg-Ser-Ser, Leu-Arg-Arg-Ser-Ser, or Ser-Leu-Arg-Arg-Ser-Ser; and B represents Asn, Asn-Ser, Asn-Ser-Phe, Asn-Ser-Phe-Arg, or Asn-Ser-Phe-Arg-Tyr; with the proviso that alpha -hANP(1-28), alpha -rANP(1-28), alpha -rANP(4-28), alpha -rANP(5-27), alpha -rANP(5-25), and alpha -rANP(3-28) are excluded from the compounds represented by the formula are disclosed along with methods of using these compounds.
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