发明名称 Cyclic pyrophosphates of purine and pyrimidine acyclonucleosides
摘要 A compound of the formula R-CH2-O-W and its pharmaceutically acceptable salts wherein R is a purine, a substituted purine, a pyrimidine or a substituted pyrimidine, wherein the substituents on the purine or pyrimidine are selected from amino, hydroxyl, halogen, thiol or alkylthiol wherein the alkyl moiety of the alkylthiol has 1 to 6 carbon atoms; and W is <IMAGE> The compounds have antiviral activity.
申请公布号 US4670424(A) 申请公布日期 1987.06.02
申请号 US19830533676 申请日期 1983.09.19
申请人 MERCK & CO., INC. 发明人 MACCOSS, MALCOLM;TOLMAN, RICHARD
分类号 A61K31/70;A61P31/12;C07F9/6561;C07F9/6574;(IPC1-7):A61K31/52;A61K31/505;C07D473/18;C07D473/34;C07D239/55 主分类号 A61K31/70
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