发明名称 PROCESS FOR THE PREPARATION OF DICHLOROANILINE DERIVATIVES
摘要 <p>The invention provides compounds of the general formula (I) <IMAGE> (I) wherein X represents a bond or a C1-6 alkylene, C2-6 alkenylene or C2-6 alkynylene chain, and Y represents a bond, or a C1-4 alkylene, C2-4 alkenylene or C2-4 alkynylene chain with the proviso that the sum total of carbon atoms in X and Y is not more than 8; Py represents a pyridyl group optionally substituted by one or two substituents selected from halogen atoms, hydroxy, C1-3 alkyl and C1-3 alkoxy groups; and R1 and R2 each represent a hydrogen atom or a C1-3 alkyl group, with the proviso that the sum total of carbon atoms in R1 and R2 is not more than 4; and physiologically acceptable salts and solvates (e.g. hydrates) thereof. The compounds have a stimulant action at beta 2-adrenoreceptors and may be used in the treatment of diseases associated with reversible airways obstruction such as asthma and chronic bronchitis.</p>
申请公布号 GR870220(B) 申请公布日期 1987.05.28
申请号 GR19870100220 申请日期 1987.02.10
申请人 GLAXO GROUP LIMITED 发明人 LAWRENCE HENRY CHARLES LUNTS
分类号 C07D213/38;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/4418;A61K31/4425;A61P1/04;A61P11/00;A61P11/08;A61P13/02;A61P15/00;A61P25/24;A61P25/26;A61P27/02;A61P27/14;A61P29/00;A61P37/08;C07D213/30;C07D213/61;C07D213/63;C07D213/65 主分类号 C07D213/38
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