| 摘要 |
A series of nootropic compounds of the following formula: <IMAGE> and its pharmaceutically acceptable acid addition salts, wherein: R2 is hydrogen, lower alkyl, aryl which is optimally substituted, or hetaryl; R7 is hydrogen or is combined with R9 as a fused benzo-ring; R8 is hydrogen or lower alkyl; and R9 is lower alkyl, or R9 can be combined with R8 to give a 2-pyrrolidinone, a phthalimide, or isoindolone ring system. Pharmacological testing demonstrates that the series possesses cognition and memory enhancing actions and/or mild CNS simulation.
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