发明名称 |
Method for preparing (+)S-2--hydroxy-2-methyl-hexanoic acid |
摘要 |
A method for preparing an important stereo-specific intermediate in the synthesis of prostaglandin analogs is disclosed. Said intermediate is (+)S-2-hydroxy-2-methyl-hexanoic acid and is prepared via an asymmetric halolactonization reaction utilizing L-proline as the chiral agent.
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申请公布号 |
US4668822(A) |
申请公布日期 |
1987.05.26 |
申请号 |
US19860894390 |
申请日期 |
1986.08.11 |
申请人 |
MILES LABORATORIES, INC. |
发明人 |
COREY, PAUL F. |
分类号 |
C07C51/00;C07C51/09;C07C405/00;C07D207/16;C07D498/04;(IPC1-7):C07C59/01 |
主分类号 |
C07C51/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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