Penicillin derivatives

摘要

This invention provides a penicillin derivative of the formula <IMAGE> wherein R1 and R2 are the same or different and represent hydrogen, C1-6 alkyl, C1-6 hydroxyalkyl, C3-9 acyloxyalkyl, C8-13 benzyloxyalkyl, C2-7 alkoxyalkyl, C2-7 alkoxycarbonyl, C3-8 alkenyloxycarbonyl, C3-8 alkynyloxycarbonyl, phenyl, amino, cyano, formyl, trifluoromethyl, C2-6 acyl, carbamoyl, C2-7 alkylcarbamoyl, benzyloxycarbonylamino, C2-7 alkoxycarbonylamino; and R3 is hydrogen, a group for forming a pharmaceutically acceptable salt, or a penicillin carboxyl protecting group, with the proviso that both of R1 and R2 are not hydrogen or C2-7 alkoxycarbonyl at the same time and that when one of R1 and R2 is hydrogen, the other is not C2-7 alkoxycarbonyl, or a pharmaceutically acceptable acid addition salt, process for preparing the derivative, and a pharmaceutical composition containing the derivative.