| 摘要 |
This invention relates to 2-(4-phenylpiperazinylethyl)anilines, to methods for preparing them and to their uses in medical therapy. These compounds have the following general formula <IMAGE> (I) wherein R1 represents one or more substituents selected from the group consisting of H, CH3, CF3, F, Cl, and OCH3; R2 and R3, which may be the same or different, and are selected from the group consisting of H and (C1-C4) alkoxy, or R2 and R3 taken together can form a chain selected from the group consisting of -O- (CH2)n-O-, wherein n=1 or 2 and -O-CH2-O-CH2 with the proviso that R1 is not meta CF3 when R2=R3=H, and pharmaceutically non-toxic salts thereof. The compounds of this invention are useful in the treatment of allergic and anaphylatic conditions and motion sickness.
|
