发明名称 |
UNDENATURED VIRUS-FREE BIOLOGICALLY ACTIVE PROTEIN DERIVATIVES |
摘要 |
<p>A mammalian blood protein-containing composition such as whole blood, plasma, serum, plasma concentrate, cryoprecipitate, cryosupernatant, plasma fractionation precipitate or plasma fractionation supernatant substantially free of hepatitis and other lipid coated viruses with the yield of protein activity to total protein being at least 80% is disclosed. The protein-containing composition is contacted with di- or trialkylphosphate, preferably a mixture of trialkylphosphate and detergent, usually followed by removal of the di- or trialkylphosphate.</p> |
申请公布号 |
CA1221910(A) |
申请公布日期 |
1987.05.19 |
申请号 |
CA19840458166 |
申请日期 |
1984.07.05 |
申请人 |
NEW YORK BLOOD CENTER, INC. |
发明人 |
NEURATH, ALEXANDER R.;HOROWITZ, BERNARD |
分类号 |
A61K39/395;A61K35/14;A61K35/16;A61K38/00;A61K38/16;A61K38/21;A61K38/43;A61L2/00;(IPC1-7):A61K35/14;A61K37/00 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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