| 摘要 |
1,135,302. Cross-linked vinyl ester or vinylene carbonate. E. MERCK A.G. 8 March, 1967 [31 March, 1966], No. 10955/67. Heading C3P. [Also in Division B1] An agent for gel chromatography consists of an oil-insoluble cross-linked copolymer which has been obtained by copolymerization, with simultaneous or subsequent cross-linking, of a vinyl ester containing up to 20 carbon atoms and/or of vinylene carbonate with at least one cross-linking vinyl or allyl compound (other than ethylidene-bis-3- (N-vinyl-2-pyrrolidone), said cross-linking compound being used in an amount of at least 1% by weight, referred to the total weight of vinyl ester and/or vinylene carbonate and of the cross-linking compound, or consists of a product obtained by the partial or complete saponification of such a cross-linked copolymer. Suitable cross-linking compounds are divinyl ethers of alkane-diols, e.g. butane- 1,4-diol divinyl ether and hexane-1,6-diol divinyl ether, divinyl ethers of oligo-ethyleneglycols, e.g. diethylene glycol divinyl ether, tetraallyl silane, dimethyl diallyl silane and compounds containing an epoxy or aldehyde group. Suitable vinyl esters are vinyl acetate, vinyl propionate and mixtures of vinyl acetate and/or vinyl propionate with a vinyl ester of a fatty acid of 12 to 18 carbon atoms, e.g. vinyl stearate. The copolymers may be saponified with an acid or alkaline medium or by heating with water. In the examples are used: polyvinyl alcohol, azo-isobutyrodinitrile, disodium hydrogen phosphate, sodium dihydrogen phosphate, amyl alcohol, benzoyl peroxide, sodium alkylsulphonates, potassium peroxydisulphate, sodium dithionite, sodium phosphate, hexanol, α-n-butyl ether, n-heptanol, n-octane and polyvinyl pyrrolidone solution. In Examples 13 and 14 and 15 divinyl sulphone and adipic acid divinyl ester are used. |
