| 发明名称 |
IMMUNOLOGICAL COMPOSITION AND METHOD FOR HEPATITIS B VIRUS |
| 摘要 |
A composition for eliciting production of antibody to hepatitis B surface antigen and method of neutralizing the infectivity of hepatitis type B virus. A cyclic polypeptide is prepared having a disulfide bond in a hydrophilic region, namely residues 117-137 or 122-137 and an amino acid sequence unique from that associated with the native 25,000 molecular weight polypeptide derived from hepatitis B surface antigen. |
| 申请公布号 |
DE3275998(D1) |
申请公布日期 |
1987.05.14 |
| 申请号 |
DE19823275998 |
申请日期 |
1982.12.21 |
| 申请人 |
BAYLOR COLLEGE OF MEDICINE |
发明人 |
DREESMAN, GORDON RONALD;SPARROW, JAMES THOMAS;PETERSON, DARRELL LYNN;HOLLINGER, FREDERICK BLAINE;MELNICK, JOSEPH LOUIS |
| 分类号 |
A61K39/29;A61K38/00;A61P37/00;C07K14/02;(IPC1-7):C07K7/64;A61K37/02;A61K39/00;G01N33/53 |
主分类号 |
A61K39/29 |
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