发明名称 PROCESS FOR PREPARING 5-(LOWER ALKYL)-1,6 NAPHTHYRIDIN-2(1H)-ONES
摘要 The title compds. (I) or its acid addn. salts are prepd. by reacting (II) with formamidine, ammonia or its salt. R, R1 and R2 are lower alkyl; R'=H or Me; R"=H or lower alkyl; Q=H, OH, amino, cyano, carbamyl, carboxy or amino carbamyl; Q'=H or cyano. (I) are useful as cardiotonic drugs. The rxn. performed in the anhydrous condition. Q is carboxy and carbamyl compds. are produced from hydrolysis of Q is cyano compds., if necessary.
申请公布号 KR870000959(B1) 申请公布日期 1987.05.14
申请号 KR19830003601 申请日期 1983.08.01
申请人 STERLING DRUG INC. 发明人 LESHER GEORGE Y.;SINGH BALDEV
分类号 A61K31/435;A61P9/04;C07D213/64;C07D213/80;C07D213/82;C07D213/85;C07D471/04;(IPC1-7):C07D471/04 主分类号 A61K31/435
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