| 摘要 |
NEW MATERIAL:A compound expressed by formula I [m is 2-4; A and B represent O or S; R1 and R2 are different from each other and represent the formula -CONHR3 (R3 is 10-22C alkyl), formula II (n is 2-10; R4-R6 represent H, lower alkyl, heteroaromatic ring in combination with the adjacent N, etc.); X represents halogen atom, lower alkylsulfonyloxy, etc.] or salt thereof. EXAMPLE:dl-(trans-3-N-Heptadecylcarbamoyloxy-tetrahydropyran-2-yl) methyl-2- thiazolylethyl phosphate. USE:An antishock, antithrombotic agent, etc. PREPARATION:For example, a compound expressed by formula III is reacted with a compound expressed by formula IV (example; 2-bromoethyl phosphorodichloridate, etc.) to obtain a compound expressed by formula V, followed by reacting with an amine expressed by formula VI. The starting material is a novel compound and obtained from, for example 3,4-dihydro-2H- pyran, etc.
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