发明名称 |
Process for producing highly purified HCG |
摘要 |
Crude HCG is purified by extracting with a neutral or weakly basic aqueous solution containing lower aliphatic alcohol and soluble salt, adding lower aliphatic alcohol to the extracted solution to form precipitates and the precipitates containing high purity of HCG are collected. This precipitates can be further purified by dissolving in a buffer solution, contacting the solution with a weak anion exchanger and eluting the exchanger with said buffer solution containing added salt.
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申请公布号 |
US4665161(A) |
申请公布日期 |
1987.05.12 |
申请号 |
US19860857511 |
申请日期 |
1986.04.21 |
申请人 |
JAPAN CHEMICAL RESEARCH CO., LTD. |
发明人 |
YUKI, YOSHIKAZU;NISHIMURA, TOYOHIKO;HIRATANI, HAJIME |
分类号 |
A61K35/22;A61K38/24;A61P5/00;C07K1/30;C07K14/435;C07K14/575;C07K14/59;C07K14/61;(IPC1-7):C07K3/12 |
主分类号 |
A61K35/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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