| 摘要 |
<p>A method of alleviating the accumulation of waste nitrogen in human beings is disclosed, wherein phenylbutyrate, or even numbered conger thereof, is administered to a patient having such waste nitrogen accumulation. The phenylbutyrate or other compound is broken down by beta-oxidation to eventually yield phenylacetate, which is known to be useful for removing waste nitrogen from the blood stream. The present invention provides a solution to the offensive odor of phenylacetate,which is unpalatable to patients, and also can eliminate peaks and valleys of drug levels in the patient, due to the gradual formation of the desired compound phenylacetate in the patient's body.</p> |
