发明名称 |
Biomedical silver-109m isotope generator |
摘要 |
A method, composition of matter, and apparatus for producing substantially pure Ag-109m for use in biomedical imaging techniques. Cd-109, which decays with a half-life of 453 days to Ag-109m is loaded onto an ion exchange column consisting of particulate tin phosphate. After secular equilibrium is reached in about ten minutes, Ag-109m may be selectively eluted from the column by means of a physiologically acceptable aqueous buffered eluent solution of sodium thiosulfate, and either ascorbic acid or dextrose. The breakthrough of toxic Cd-109 is on the order of 1x10-7, which is sufficiently low to permit administration of the Ag-109m-containing eluate, with but a minor pH adjustment, directly to a human patient within a matter of seconds.
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申请公布号 |
US4664892(A) |
申请公布日期 |
1987.05.12 |
申请号 |
US19850708625 |
申请日期 |
1985.03.05 |
申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY |
发明人 |
WANEK, PHILIP M.;STEINKRUGER, FREDERICK J.;MOODY, DAVID C. |
分类号 |
G21G4/08;(IPC1-7):C09K11/00;H01L25/00 |
主分类号 |
G21G4/08 |
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