发明名称 N-SUBSTITUTED ALPHA-AMINO ACIDS
摘要 Compounds of the formula I <IMAGE> (I) in which the carboxyl group on carbon atom 3 is orientated in the endo-position relative to the bicyclic ring system of cis-configuration, and in which R1 denotes hydrogen, allyl, vinyl or a side-chain of a naturally occurring alpha -aminoacid, which may be protected, R2 denotes hydrogen, alkyl, alkenyl or aralkyl, Y denotes hydrogen or hydroxyl and Z denotes hydrogen, or Y and Z together denote oxygen, and X denotes alkyl, alkenyl or cycloalkyl, or aryl which is optionally mono-, di- or tri-substituted by alkyl, alkoxy, hydroxyl, halogen, nitro, amino, alkylamino, dialkylamino or methylenedioxy, or denotes indol-3-yl, a process for their preparation, agents containing these compounds and their use.
申请公布号 AU6851087(A) 申请公布日期 1987.05.07
申请号 AU19870068510 申请日期 1987.02.04
申请人 HOECHST A.G. 发明人 VOLKER TEETZ;ROLF GEIGER;HANSJORG URBACH;REINHARD BECKER;BERNWARD SCHOLKENS
分类号 C07C227/08;A61K31/40;A61K31/403;A61K38/00;A61P9/12;C07C227/10;C07C227/16;C07C229/36;C07C237/06;C07D209/52;C07D451/04;C07K5/02;C07K5/06 主分类号 C07C227/08
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