摘要 |
<p>An assay system for determination of an analyte. The system includes liposomes having surface-bound, analyte-related binding molecules and entrapped reporter molecules, and a cellulose acetate surface reagent having surface molecules adapted to bind the liposomes to the reagent in proportion to the amount of analyte present. The reagent is prepared, according to the invention, by treating a cellulose acetate substrate with a base, to form a hydrophilic, hydroxyl-group shell on the substrate surface, reacting the modified substrate with a bifunctional reagent in an organic solvent, and coupling the surface molecules to the activated substrate in an aqueous solution.</p> |