| 摘要 |
<p>There are disclosed compounds of the formula <CHEM> wherein R represents formula III or represents -CHR<1>-CHR<2>- wherein R<1> and R<2> taken together represent formula II or IV <CHEM> with the proviso that the sum of o and p in formula III and in formula IV where Y is -(CH2)0- is not zero; R<3> is unsubstituted or substituted phenyl, 2-pyridinyl, 2-pyrimidinyl, 2-pyrazinyl or 3-pyridazinyl, where the substituents are selected from the group lower alkyl, lower alkoxy, halo, cyano, nitro and trifluoromethyl, with the proviso that when R<1> and R<2> taken together represent formula II in which X is O,methylene or dimethylene, R<3> is other than unsubstituted or substituted phenyl, 2-pyridinyl or 2-pyrimidinyl; Y is -(CH2)0- or vinylene; X is lower alkylene, vinylene or O; m is 2 - 4; n is 1 - 3; o is 0 - 3; p is 0 - 4; ..... represents a single or double bond; and the pharmaceutically acceptable salts thereof and their use as antipsychotic/anxiolytic agents having a low liability for extrapyramidal side effects.</p> |
