发明名称 Acylaminoalkylpyridines ad use in treatment of inflammation and allergy reactions
摘要 The compounds of this invention are acylaminoalkylpyridines representd by the formula <IMAGE> wherein: R1 and R2 are the same or different members of the group consisting of halo, phenyl, substituted phenyl and a <IMAGE> group wherein n, m and p are independently an integer of from 1 to 8 provided n+m+p is equal to or less than 10; X is thio, sulfinyl or sulfonyl; Alk1 is straight or branched chain lower alkylene of 1 to 6 carbon atoms, R3 is lower alkyl, Alk2 is straight or branched chain alkylene of 1 to 4 carbon atoms; R4 is selected from the group consisting of hydrogen, halo, hydroxy, lower alkyl and lower alkoxy; and the pharmaceutically acceptable salts thereof. The compounds of the present invention are useful in the treatment of inflammation, allergy and hypersensitivity reactions and other disorders of the immune system.
申请公布号 US4663333(A) 申请公布日期 1987.05.05
申请号 US19850809955 申请日期 1985.12.20
申请人 G. D. SEARLE & CO. 发明人 MUELLER, RICHARD A.;PARTIS, RICHARD A.;DEASON, JAMES R.
分类号 A61K31/44;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/4418;A61P29/00;A61P37/08;C07D213/40;(IPC1-7):A61K31/44;C07D211/72;C07D211/70 主分类号 A61K31/44
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