发明名称 |
Tetrazole derivatives, anti-ulcer composition containing the same and method for treating ulcers |
摘要 |
Tetrazole derivatives of the formula: <IMAGE> [I] wherein R1 is an optional defined substituent; A is sulfur or a lower alkylene-thio, l is 0 or 1; B is a lower alkylene; R2 is hydroxy, a lower alkoxy, or a group: <IMAGE> wherein R3 and R4 are optional defined substituents, or the R3 and R4 may combine together with the nitrogen atom to which they are joined to form a defined heterocyclic group, and a pharmaceutically acceptable salt thereof, which have prophylactic or therapeutic activities against peptic and/or duodenal ulcers and also anti-inflammatory activity and are useful as an anti-ulcer or anti-inflammatory drug; processes for the preparation of the tetrazole derivatives; and pharmaceutical composition containing said tetrazole derivatives.
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申请公布号 |
US4663323(A) |
申请公布日期 |
1987.05.05 |
申请号 |
US19840609333 |
申请日期 |
1984.05.11 |
申请人 |
OTSUKA PHARMACEUTICAL CO., LTD. |
发明人 |
UCHIDA, MINORU;NISHI, TAKAO;NAKAGAWA, KAZUYUKI |
分类号 |
C07D257/04;(IPC1-7):C07D257/04;C07D413/06;C07D413/12;A61K31/535 |
主分类号 |
C07D257/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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