Use of azabicloalkylbenzamides in the treatment of gastrointestinal motility disorders, migraine, emesis, cluster headaches, trigeminal neuralgia and arrhythmia.

摘要

A method of treatment of undesirable actions of 5-HT on the gastro-intestinal tract; migraine, cluster headaches and trigeminal neuralgia, cytotoxic agent or radiation induced nausea and vomiting and/or arrhythmia in mammals, including humans, which method comprises administering an efffective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof: <CHEM> wherein: R is amino or C1-7 acylamino; X is chloro, bromo or C1-6 alkylthio; and p is 0 or 1; novel compounds within formula (I) wherein X is bromo or C1-6 alkylthio, a process for their prepar-ation and their use as pharmaceuticals.