摘要 |
There are described compounds of the formula <IMAGE> where each X is independently H, halogen, loweralkyl, loweralkoxy or OH; m is 1 or 2; and R is -H, =O, <IMAGE> =CH(CH2)nNR1CH3, -CH2(CH2)nNR1R2, =N-OH, =N-OCH2(CH2)nNR1R3, <IMAGE> =N-OCH2CHOHCH2NR1R3, -NR2R3, -OH or -OCH2(CH2)nNR1R2, n being 1 or 2, R1 being loweralkyl, R2 being H, loweralkyl, loweralkanoyl, arylloweralkyl, arylloweralkanoyl, diarylloweralkyl, diarylloweralkanoyl, -CO2C2H5 or -CN, and R3 being H, loweralkyl, arylloweralkyl or diarylloweralkyl, or a pharmaceutically acceptable acid addition salt thereof, which are useful as antihypertensive, anticonvulsant, analgesic and antidepressant agents. |