发明名称 TABLET PRODUCTION
摘要 PURPOSE:A specific organic acid and polyethylene glycol (PEG) are melt-mixed at a specific temperature and the mixture is cooled down, as it is stirred in a fluidized bed, to form a powder, then the powder is combined with sodium bicarbonate and sodium carbonate and the mixture is tabletted. CONSTITUTION:An organic acid, which is substantially free from water or does not liberate water of crystallization lower than 50 deg.C such as citric, malic or succinic acid is melted together with PEG at 60-100 deg.C and cooled down in a fluidized bed such as an apparatus which is a cylinder of a round cross section and equipped with the rotation shaft at its center and a stirring blades such as paddles or propeller at the bottom to form a powder. The power is mixed with sodium bicarbonate and sodium carbonate and tabletted to give tablets of a foaming composition which has good storability and readily dissolves in water, as liberating carbon dioxide. The amount of PEG is 1 to 20pts.wt., preferably 2-10pts.wt. per 100pts.wt. of the organic acid.
申请公布号 JPS6289616(A) 申请公布日期 1987.04.24
申请号 JP19850230820 申请日期 1985.10.16
申请人 KAO CORP 发明人 MATSUMOTO TADAO;ISHIKAWA YUKIMASA;ABE KUNIHIRO
分类号 A61K9/46;A61K8/00;A61K8/02;A61K8/36;A61K8/362;A61K8/86;A61Q19/10;C11D7/12;C11D7/26;C11D7/60;C11D17/06 主分类号 A61K9/46
代理机构 代理人
主权项
地址