Method of enhancing tissue plasminogen activator and single chain urokinase plasminogen activator production.

摘要

The invention concerns a method of enhancing the production of tissue plasminogen activator (t-PA) and/or single chain urokinase plasminogen activator (SCU-PA) in normal human diploid lung fibroblast cell cultures in a serum-free medium comprising adding to said culture heparin or low molecular weight heparin and an endothelial cell growth factor.