发明名称 |
2-(4,5-Dihydro-1H-imidazol-2-yl)-2,3-dihydroindole derivatives and their application as alpha 2 receptor antagonist or alpha 1 receptor agonists |
摘要 |
Derivatives of formula (I) <IMAGE> in which X denotes a hydrogen or halogen atom, an alkoxy radical, an alkyl radical or an allyloxy radical, and R denotes a linear or branched alkyl radical, a cycloalkylalkyl radical, an alkenyl radical, an arylalkyl radical which can bear one or more substituents chosen from halogen atoms and methyl, methoxy and methylenedioxy radicals, or alternatively an optionally substituted phenyl radical, as well as the addition salts thereof with pharmaceutically acceptable acids produce an alpha 2-receptor antagonist effect.
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申请公布号 |
US4659731(A) |
申请公布日期 |
1987.04.21 |
申请号 |
US19860826500 |
申请日期 |
1986.02.05 |
申请人 |
SYNTHELABO |
发明人 |
BIGG, DENIS;MENIN, JACQUES;MALOIZEL, CHRISTIAN;MERLY, JEAN |
分类号 |
C07D209/42;C07D403/04;(IPC1-7):A61K31/415;C07D403/00 |
主分类号 |
C07D209/42 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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